1 CYP 1 A 2 polymorphism - 1545 C > T ( rs 2470890 ) is associated with side effects of clozapine

نویسندگان

  • Merja Viikki
  • Olli Kampman
  • Niko Seppälä
  • Nina Mononen
  • Terho Lehtimäki
  • Esa Leinonen
چکیده

University of Tampere, Medical School, 33014 University of Tampere, Finland Tampere Mental Health Centre, Hallituskatu 8 B, 33200 Tampere, Finland Seinäjoki Hospital District, Department of Psychiatry, Seinäjoki, Finland. Department of Psychiatry, Satakunta Hospital District, Fi-28500 Pori , Finland Department of clinical chemistry, Fimlab Laboratories, School of Medicine University of Tampere, Tampere, Finland Tampere University Hospital, Department of Psychiatry, Tampere, Finland

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منابع مشابه

CYP1A2 polymorphism −1545C > T (rs2470890) is associated with increased side effects to clozapine

BACKGROUND Cytochrome P450 1A2 gene (CYP1A2) polymorphisms have been suggested to be associated with increased side effects to antipsychotics. However, studies on this are scarce and have been conducted with either various antipsychotics or only in small samples of patients receiving clozapine. The aim of the present study was to test for an association between the CYP1A2 -1545C > T (rs2470890)...

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تاریخ انتشار 2013